BIO-478 Pharmacology and pharmacokinetics

ROOM AAC 137 / Tuesday 8-10 am / Wednesday 8-10 am / 1hour of library assignment

Goals of the course

This course introduces the basic concepts of pharmacology, including pharmacodynamics, pharmacokinetics, pharmacogenetics and chronopharmacology. These topics will be illustrated by a range of concrete biomedical examples as well as by a series of exercises on drug-receptor interaction.

Content of the course

- Introduction to Pharmacology

- Pharmacodynamics: Drug-target interaction, quantitative description of ligand binding, relationship between ligand binding and functional effect; exercises

- Classes of drug targets: functional and structural aspects, examples

- Pharmacokinetics: principal models and parameters,
Drug Absorption, Distribution, Metabolism and Excretion (ADME)

- Chronopharmacology: effect of circadian rhythm on drug action

- Pharmacogenetics: candidate genes for variable drug response